ABSTRACT
Objective To determine the association of the oxygenation index and lactate levels with neurogenic pulmonary edema (NPE) in patients with intracerebral hemorrhage. Methods We retrospectively evaluated 116 patients with intracerebral hemorrhage, who were admitted to the First Affiliated Hospital of China Medical University between May 2014 and May 2017. Patients were divided into NPE and non-NPE groups and the groups were compared to identify the factors associated with the occurrence of NPE. Results The oxygenation index, lactate level, pH, PC02, brain natriuretic peptide (BNP) level, and Glasgow coma scale were significantly different between the NPE and non-NPE groups (all P ＜ 0. 05). Logistic regression analysis showed that the oxygenation index (B =0. 049; OR =1. 05;p =0. 04) and lactic acid level (B =-5. 855; OR =0. 003;P=0. 01) were associated with the occurrence of NPE in patients with intracerebral hemorrhage. Conclusion A decrease in oxygenation index and an increase in serum lactate level are directly associated with the occurrence of NPE in patients with intracerebral hemorrhage.